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CBD and Alcohol: What Happens When You Mix Them

Introduction

Given the benefits of CBD, it’s no surprise how it has made its way into a lot of routines lately. These can be sublingual methods, vapes or ingestion through food & drinks. And in a culture where a glass of wine or a toast is rarely far off, it’s fair to question: “Is it safe to mix CBD and alcohol?” 

Honestly, the answer is not a clear cut yes or no. In this guide, we will see what the research says about CBD & alcohol, what happens in your body when the two meet, and practical considerations to move ahead.

CBD and alcohol taken together may intensify each other’s sedative effects. Most healthy adults report no serious problems from combining them in moderate amounts, but the combination reduces alertness more than either alone. Research into CBD as a support tool for reducing alcohol consumption is early-stage but promising.

What happens when you take CBD and alcohol together?

Both CBD and alcohol have sedative properties that can make you feel calm & relaxed. Therefore, taking them together may make those effects more noticeable. You might feel unusually drowsy, dizzy, light-headed, or less alert than you expected. 

That said, there is not enough human research to say exactly how CBD and alcohol interact. The evidence we do have is limited, and some of it is decades old.

One of the most-cited studies on the combination was the 1979 study published on NIH:

The Research – Carlini, E.A., Zwicker, A.P. et al. (1979) 

Who: P Consroe, E A Carlini, A P Zwicker, L A Lacerda 

The study: 6 male and 4 female healthy volunteers were given CBD (200 MG), alcohol, oral placebo, and CBD+ alcohol. The dosages were spaced one week apart.

What they found: Participants who received CBD with alcohol showed greater impairment in motor performance than when they received CBD alone. Also, they reported lower blood alcohol levels.

Why this matters: While the study has promising results, it had a small number of participants. And a 200 mg CBD dose is way higher than any CBD supplement one would consume. 

Source: Interaction of cannabidiol and alcohol in humans (PubMed)

So, the study is useful as an early warning signal, but it does not give us a clear picture of what happens when someone has a typical CBD product with one alcoholic drink. 

NOTE: Neither CBD nor alcohol is recommended before driving, operating machinery, swimming, or any activity where reduced coordination or alertness could put you at risk.

Does CBD cancel out alcohol?

No. CBD should not be used to cancel out, reverse, or sober up from alcohol. There is no strong evidence that taking CBD meaningfully reduces alcohol intoxication or makes it safer to drink. 

In fact, even in the 1979 study we discussed above, the participants were not less impaired simply because their blood alcohol levels were lower. Even though preliminary studies are exploring CBD for alcohol use disorder, it is not an antidote to reverse intoxication or make drinking safe.

So, if you’ve been drinking, don’t take CBD expecting it to bring you back to sober. Time is what allows your body to process alcohol. CBD isn’t a shortcut around that process. 

Does CBD help with hangovers?

Again, CBD is not a direct cure for a hangover. But it can prevent symptoms of being high like nausea, headaches, and hangover-induced anxiety. 

Users report that consuming CBD on the morning after the hangover helped them with these symptoms. These reports are anecdotal, though, and should not be treated as evidence that CBD actually treats hangovers.

So, if you do take CBD after being drunk, go in with the right expectations.

Can CBD help reduce alcohol consumption — what the research shows

This is where the research gets genuinely interesting, but it’s important to frame it right. CBD is being studied as a potential support tool for people struggling with alcohol. That’s different from saying CBD treats alcohol use disorder.

Two studies worth knowing about:

A 2024 study published via ScienceDirect reported that CBD reduced binge-like alcohol drinking in animal models. The effect, in animal studies, appeared to involve how the brain responds to cues associated with alcohol — essentially, CBD seemed to dampen the cycle of craving and consumption.

Another 2019 study in Neuropsychopharmacology looked at people with alcohol use disorder and found that CBD was associated with reduced craving when participants were exposed to alcohol-related cues, compared with a placebo. The sample was small, the effects modest, and the work is best understood as proof-of-concept rather than confirmation.

These are promising signals, but they are signals, not proof. To date, no CBD product is approved to treat alcohol use disorder. If you or someone you know is struggling with alcohol, talk to a doctor.

Practical considerations for CBD and Alcohol

If you drink socially and use CBD, here’s what to keep in mind:

  • Spacing matters. Using CBD in the morning and drinking in the evening is different from taking both at the same time. The further apart, the less interaction.
  • Sedation stacks. If you combine them, expect drowsiness. Plan accordingly. Don’t drive.
  • Not everyone responds the same. Body weight, metabolism, tolerance, and the amount of each substance all play a role.
  • Liver processing. CBD and alcohol are both metabolized by the liver. If you have liver issues or are on medication, talk to your doctor first.
  • CBD works best on its own. If you’re taking CBD as part of a daily wellness routine, it has more benefit as a standalone supplement than mixed with alcohol.

Frequently Asked Questions (FAQs)

Yes, you may, but the combination may amplify sedative effects like pronounced drowsiness, fatigue, and dizziness.

No clinical research confirms this. However, some users report benefit from CBD for morning-after nausea and headache.

Early research is promising but preliminary. No CBD product is approved for alcohol use disorder — speak with a healthcare professional for support.

Since CBD doesn’t come under the purview of narcotics law, it is 100% safe & legal in Georgia, provided that it meets the standard regulatory thresholds for THC content.

Conclusion

CBD and alcohol aren’t a dangerous combination for most healthy adults if taken in moderate amounts. But combining them isn’t necessary or recommended either. 

The most consistent effect of the two together is intensified sedation, not any meaningful reduction in alcohol’s effects. If your goal is to feel the benefits of CBD, it tends to work best as a standalone supplement.

If you are looking for a clean, well-made CBD supplement, then start with CBD oil. You can take it as part of your daily routine on drinking or non-drinking days. Explore your options today at I Love Joint.

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